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Mitotic CDK promotes replisome disassembly, fork breakage, and complex DNA rearrangements

DNA replication errors generate complex chromosomal rearrangements and thereby contribute to tumorigenesis and other human diseases. One mechanism that triggers these errors is mitotic entry before the completion of DNA replication. To address how mitosis might impact DNA replication, we used Xenopu...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Deng, Lin, Wu, R. Alex., Sonneville, Remi, Kochenova, Olga V., Labib, Karim, Pellman, David, Walter, Johannes C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410736/
https://ncbi.nlm.nih.gov/pubmed/30849395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.12.021
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