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Mitotic CDK promotes replisome disassembly, fork breakage, and complex DNA rearrangements
DNA replication errors generate complex chromosomal rearrangements and thereby contribute to tumorigenesis and other human diseases. One mechanism that triggers these errors is mitotic entry before the completion of DNA replication. To address how mitosis might impact DNA replication, we used Xenopu...
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| Publicado no: | Mol Cell |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410736/ https://ncbi.nlm.nih.gov/pubmed/30849395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.12.021 |
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