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Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity
We have shown previously that the process of replication machinery (replisome) disassembly at the termination of DNA replication forks in the S-phase is driven through polyubiquitylation of one of the replicative helicase subunits (Mcm7) by Cul2(LRR1) ubiquitin ligase. Interestingly, upon inhibition...
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| Pubblicato in: | Life Sci Alliance |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6464043/ https://ncbi.nlm.nih.gov/pubmed/30979826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900390 |
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