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The ubiquitin ligase TRAIP: double-edged sword at the replisome

In preparation for cell division, the genome must be copied with high fidelity. However, replisomes often encounter obstacles, including bulky DNA lesions caused by reactive metabolites and chemotherapeutics, as well as stable nucleoprotein complexes. Here, we discuss recent advances in our understa...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Wu, R. Alex, Pellman, David S., Walter, Johannes C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856240/
https://ncbi.nlm.nih.gov/pubmed/33317933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2020.11.007
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