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Synthesis and mechanistic investigations of pH-responsive cationic poly(aminoester)s

The synthesis and degradation mechanisms of a class of pH-sensitive, rapidly degrading cationic poly(α-aminoester)s are described. These reactive, cationic polymers are stable at low pH in water, but undergo a fast and selective degradation at higher pH to liberate neutral diketopiperazines. Related...

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Pubblicato in:Chem Sci
Autori principali: Blake, Timothy R., Ho, Wilson C., Turlington, Christopher R., Zang, Xiaoyu, Huttner, Melanie A., Wender, Paul A., Waymouth, Robert M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society of Chemistry 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8157522/
https://ncbi.nlm.nih.gov/pubmed/34122796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc05267d
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