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Double p52Shc/p46Shc Rat Knockout Demonstrates Severe Gait Abnormalities Accompanied by Dilated Cardiomyopathy

The ubiquitously expressed adaptor protein Shc exists in three isoforms p46Shc, p52Shc, and p66Shc, which execute distinctly different actions in cells. The role of p46Shc is insufficiently studied, and the purpose of this study was to further investigate its functional significance. We developed un...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Miller, Bradley, Kostrominova, Tatiana Y., Geurts, Aron M., Sorokin, Andrey
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8155973/
https://ncbi.nlm.nih.gov/pubmed/34063460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22105237
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