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p46Shc Inhibits Thiolase and Lipid Oxidation in Mitochondria
Although the p46Shc isoform has been known to be mitochondrially localized for 11 years, its function in mitochondria has been a mystery. We confirmed p46Shc to be mitochondrially localized and showed that the major mitochondrial partner of p46Shc is the lipid oxidation enzyme 3-ketoacylCoA thiolase...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933453/ https://ncbi.nlm.nih.gov/pubmed/27059956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.695577 |
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