Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

Shc proteins are targets of activated tyrosine kinases and are implicated in the transmission of activation signals to Ras. The p46shc and p52shc isoforms share a C-terminal SH2 domain, a proline- and glycine-rich region (collagen homologous region 1; CH1) and a N-terminal PTB domain. We have isolat...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Migliaccio, E, Mele, S, Salcini, A E, Pelicci, G, Lai, K M, Superti-Furga, G, Pawson, T, Di Fiore, P P, Lanfrancone, L, Pelicci, P G
Format: Artigo
Langue:Inglês
Publié: 1997
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169672/
https://ncbi.nlm.nih.gov/pubmed/9049300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.4.706
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