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Modelling the p53/p66Shc Aging Pathway in the Shortest Living Vertebrate Nothobranchius Furzeri

Oxidative stress induced by reactive oxygen species (ROS) increases during lifespan and is involved in aging processes. The p66Shc adaptor protein is a master regulator of oxidative stress response in mammals. Ablation of p66Shc enhances oxidative stress resistance both in vitro and in vivo. Most im...

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書誌詳細
出版年:Aging Dis
主要な著者: Priami, Chiara, De Michele, Giulia, Cotelli, Franco, Cellerino, Alessandro, Giorgio, Marco, Pelicci, Pier Giuseppe, Migliaccio, Enrica
フォーマット: Artigo
言語:Inglês
出版事項: JKL International LLC 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365960/
https://ncbi.nlm.nih.gov/pubmed/25821638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14336/AD.2014.0228
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