The p52 isoform of SHC1 is a key driver of breast cancer initiation

BACKGROUND: SHC1 proteins (also called SHCA) exist in three functionally distinct isoforms (p46SHC, p52SHC, and p66SHC) that serve as intracellular adaptors for several key signaling pathways in breast cancer. Despite the broad evidence implicating SHC1 gene products as a central mediator of breast...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res
Main Authors: Wright, Kevin D., Miller, Bradley S., El-Meanawy, Sarah, Tsaih, Shirng-Wern, Banerjee, Anjishnu, Geurts, Aron M., Sheinin, Yuri, Sun, Yunguang, Kalyanaraman, Balaraman, Rui, Hallgeir, Flister, Michael J., Sorokin, Andrey
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570928/
https://ncbi.nlm.nih.gov/pubmed/31202267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-019-1155-7
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