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A T5 Exonuclease-Based Assay for DNA Topoisomerases and DNA Intercalators

[Image: see text] DNA topoisomerases, essential enzymes to all living organisms, are important targets of certain antibiotics and anticancer drugs. Although efforts have been taken to identify new inhibitors targeting DNA topoisomerases, limited high throughput screening (HTS) studies have been cond...

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Veröffentlicht in:ACS Omega
Hauptverfasser: Deng, Zifang, Leng, Fenfei
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2021
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154156/
https://ncbi.nlm.nih.gov/pubmed/34056374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00962
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