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Dasatinib–SIK2 Binding Elucidated by Homology Modeling, Molecular Docking, and Dynamics Simulations

[Image: see text] Salt-inducible kinases (SIKs) are calcium/calmodulin-dependent protein kinase (CAMK)-like (CAMKL) family members implicated in insulin signal transduction, metabolic regulation, inflammatory response, and other processes. Here, we focused on SIK2, which is a target of the Food and...

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Bibliografische gegevens
Gepubliceerd in:ACS Omega
Hoofdauteurs: Shi, Mingsong, Wang, Lun, Li, Penghui, Liu, Jiang, Chen, Lijuan, Xu, Dingguo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2021
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153941/
https://ncbi.nlm.nih.gov/pubmed/34056256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c00947
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