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Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes
BACKGROUND: An important mechanism of endocrine activity is chemicals entering target cells via transport proteins and then interacting with hormone receptors such as the estrogen receptor (ER). α-Fetoprotein (AFP) is a major transport protein in rodent serum that can bind and sequester estrogens, t...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851483/ https://ncbi.nlm.nih.gov/pubmed/24266910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S14-S6 |
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