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Binding interactions of epididymal protease inhibitor and semenogelin-1: a homology modeling, docking and molecular dynamics simulation study

Epididymal protease inhibitor (EPPIN) that is located on the sperm surface and specific to the male reproductive system is a non-hormonal contraceptive target, since the binding of EPPIN with the seminal plasma protein semenogelin-1 (SEMG1) causes a loss of sperm function. Here, we investigated the...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Shan, Changyu, Li, Hongwei, Zhang, Yuping, Li, Yuyan, Chen, Yingchun, He, Wei
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686837/
https://ncbi.nlm.nih.gov/pubmed/31404433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.7329
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