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Microscopic Binding of M5 Muscarinic Acetylcholine Receptor with Antagonists by Homology Modeling, Molecular Docking and Molecular Dynamics Simulation

By performing homology modeling, molecular docking, and molecular dynamics (MD) simulations, we have developed three-dimensional (3D) structural models of M5 muscarinic acetylcholine receptor (mAChR) and two complexes for M5 mAChR binding with antagonists SVT-40776 and Solifenacin in the environment...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huang, Xiaoqin, Zheng, Guangrong, Zhan, Chang-Guo
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257414/
https://ncbi.nlm.nih.gov/pubmed/22185605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp210579b
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