Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy

Schwann cells produce a considerable amount of lipids and proteins to form myelin in the PNS. For this reason, the quality control of myelin proteins is crucial to ensure proper myelin synthesis. Deletion of serine 63 from P0 (P0S63del) protein in myelin forming Schwann cells causes Charcot-Marie-To...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Sidoli, Mariapaola, Reed, Chelsey B., Scapin, Cristina, Paez, Pablo, Cavener, Douglas R., Kaufman, Randal J., D'Antonio, Maurizio, Feltri, M. Laura, Wrabetz, Lawrence
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2021
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152608/
https://ncbi.nlm.nih.gov/pubmed/33879538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2384-20.2021
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