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Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy

Schwann cells produce a considerable amount of lipids and proteins to form myelin in the PNS. For this reason, the quality control of myelin proteins is crucial to ensure proper myelin synthesis. Deletion of serine 63 from P0 (P0S63del) protein in myelin forming Schwann cells causes Charcot-Marie-To...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Sidoli, Mariapaola, Reed, Chelsey B., Scapin, Cristina, Paez, Pablo, Cavener, Douglas R., Kaufman, Randal J., D'Antonio, Maurizio, Feltri, M. Laura, Wrabetz, Lawrence
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152608/
https://ncbi.nlm.nih.gov/pubmed/33879538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2384-20.2021
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