Calcineurin Activity Is Increased in Charcot-Marie-Tooth 1B Demyelinating Neuropathy

Schwann cells produce a considerable amount of lipids and proteins to form myelin in the PNS. For this reason, the quality control of myelin proteins is crucial to ensure proper myelin synthesis. Deletion of serine 63 from P0 (P0S63del) protein in myelin forming Schwann cells causes Charcot-Marie-To...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sidoli, Mariapaola, Reed, Chelsey B., Scapin, Cristina, Paez, Pablo, Cavener, Douglas R., Kaufman, Randal J., D'Antonio, Maurizio, Feltri, M. Laura, Wrabetz, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152608/
https://ncbi.nlm.nih.gov/pubmed/33879538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2384-20.2021
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