Preservation of Quaternary Structure in Thermostable, Lyophilized Filovirus Glycoprotein Vaccines: A Search for Stability-Indicating Assays

The filoviruses Zaire ebolavirus (EBOV), Marburg marburgvirus (MARV), and Sudan ebolavirus (SUDV) are some of the most lethal infectious agents known. To date, the Zaire ebolavirus vaccine (ERVEBO®) is the only United States Food and Drug Administration (FDA) approved vaccine available for any speci...

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Foilsithe in:J Pharm Sci
Main Authors: Preston, Kendall B., Monticello, Connor R., Wong, Teri Ann S., To, Albert, Donini, Oreola, Lehrer, Axel T., Randolph, Theodore W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8152177/
https://ncbi.nlm.nih.gov/pubmed/32931778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2020.09.011
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