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Proteolytic Processing of Filovirus Glycoproteins
Filoviruses (Marburg virus and Ebola virus) have a single envelope glycoprotein (GP) that initiates infection. GP is a class I fusion protein that forms trimeric spikes composed of heterodimers of the subunits GP1 and GP2. GP1 and GP2 are derived from the precursor pre-GP by furin cleavage during ex...
Guardado en:
| Publicado en: | Activation of Viruses by Host Proteases |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7122482/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-75474-1_5 |
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