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Proteolytic Processing of Filovirus Glycoproteins

Filoviruses (Marburg virus and Ebola virus) have a single envelope glycoprotein (GP) that initiates infection. GP is a class I fusion protein that forms trimeric spikes composed of heterodimers of the subunits GP1 and GP2. GP1 and GP2 are derived from the precursor pre-GP by furin cleavage during ex...

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Detalhes bibliográficos
Publicado no:Activation of Viruses by Host Proteases
Main Authors: Volchkov, Viktor, Klenk, Hans Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7122482/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-75474-1_5
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