Superior Frontal Gyrus TOMM40-APOE Locus DNA Methylation in Alzheimer’s Disease

BACKGROUND: The APOE ɛ4 allele is the strongest known genetic risk factor for sporadic Alzheimer’s disease (AD). The neighboring TOMM40 gene has also been implicated in AD due to its close proximity to APOE. OBJECTIVE: Here we tested whether methylation of the TOMM40-APOE locus may influence ApoE pr...

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Dades bibliogràfiques
Publicat a:J Alzheimers Dis Rep
Autors principals: Bezuch, Natalia, Bradburn, Steven, Robinson, Andrew C., Pendleton, Neil, Payton, Antony, Murgatroyd, Chris
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2021
Matèries:
Research Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150259/
https://ncbi.nlm.nih.gov/pubmed/34113784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-201000
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