Superior Frontal Gyrus TOMM40-APOE Locus DNA Methylation in Alzheimer’s Disease

BACKGROUND: The APOE ɛ4 allele is the strongest known genetic risk factor for sporadic Alzheimer’s disease (AD). The neighboring TOMM40 gene has also been implicated in AD due to its close proximity to APOE. OBJECTIVE: Here we tested whether methylation of the TOMM40-APOE locus may influence ApoE pr...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Alzheimers Dis Rep
Auteurs principaux: Bezuch, Natalia, Bradburn, Steven, Robinson, Andrew C., Pendleton, Neil, Payton, Antony, Murgatroyd, Chris
Format: Artigo
Langue:Inglês
Publié: IOS Press 2021
Sujets:
Research Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150259/
https://ncbi.nlm.nih.gov/pubmed/34113784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-201000
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires