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Superior Frontal Gyrus TOMM40-APOE Locus DNA Methylation in Alzheimer’s Disease
BACKGROUND: The APOE ɛ4 allele is the strongest known genetic risk factor for sporadic Alzheimer’s disease (AD). The neighboring TOMM40 gene has also been implicated in AD due to its close proximity to APOE. OBJECTIVE: Here we tested whether methylation of the TOMM40-APOE locus may influence ApoE pr...
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| 發表在: | J Alzheimers Dis Rep |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
IOS Press
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8150259/ https://ncbi.nlm.nih.gov/pubmed/34113784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-201000 |
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