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Superior Frontal Gyrus TOMM40-APOE Locus DNA Methylation in Alzheimer’s Disease

BACKGROUND: The APOE ɛ4 allele is the strongest known genetic risk factor for sporadic Alzheimer’s disease (AD). The neighboring TOMM40 gene has also been implicated in AD due to its close proximity to APOE. OBJECTIVE: Here we tested whether methylation of the TOMM40-APOE locus may influence ApoE pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Alzheimers Dis Rep
Egile Nagusiak: Bezuch, Natalia, Bradburn, Steven, Robinson, Andrew C., Pendleton, Neil, Payton, Antony, Murgatroyd, Chris
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: IOS Press 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150259/
https://ncbi.nlm.nih.gov/pubmed/34113784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ADR-201000
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