DNA methylation of TOMM40-APOE-APOC2 in Alzheimer’s disease

The apolipoprotein E (APOE) ε4 allele is the major genetic risk factor for Alzheimer’s disease (AD). Multiple regulatory elements, spanning the extended TOMM40-APOE-APOC2 region, regulate gene expression at this locus. Regulatory element DNA methylation changes occur under different environmental co...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Hum Genet
Main Authors: Shao, Yvonne, Shaw, McKenzie, Todd, Kaitlin, Khrestian, Maria, D’Aleo, Giana, Barnard, P. John, Zahratka, Jeff, Pillai, Jagan, Yu, Chang-En, Keene, C. Dirk, Leverenz, James B., Bekris, Lynn M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6466631/
https://ncbi.nlm.nih.gov/pubmed/29371683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s10038-017-0393-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados