Characterization of APOE and TOMM40 allele frequencies in the Japanese population

INTRODUCTION: Dementia is one of the major health threats to our aging society, and Alzheimer's disease (AD) is the leading cause. In Japan, ∼15% of the elderly population has dementia. The apolipoprotein E (APOE) genotype and a polymorphism (rs10524523) in the translocase of outer mitochondria...

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Pubblicato in:Alzheimers Dement (N Y)
Autori principali: Nishimura, Akira, Nonomura, Hidenori, Tanaka, Shingo, Yoshida, Michihiro, Maruyama, Yuka, Aritomi, Yutaka, Saunders, Ann M., Burns, Daniel K., Lutz, Michael W., Runyan, Grant, Lai, Eric, Budur, Kumar, Roses, Allen D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671626/
https://ncbi.nlm.nih.gov/pubmed/29124110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2017.07.003
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