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The Impact of Chlorambucil and Valproic Acid on Cell Viability, Apoptosis and Expression of p21, HDM2, BCL2 and MCL1 Genes in Chronic Lymphocytic Leukemia

Malignant cells in chronic lymphocytic leukemia (CLL) show resistance to apoptosis, as well as to chemotherapy, which are related to deletions or mutations of TP53, high expression of MCL1 and BCL2 genes and other abnormalities. Thus, the main goal of the present study was to assess the impact of ch...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cells
मुख्य लेखकों: Lipska, Katarzyna, Filip, Agata, Gumieniczek, Anna
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147495/
https://ncbi.nlm.nih.gov/pubmed/34063233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051088
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