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HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia

High performance liquid chromatography with ultra-violet detection (HPLC-UV) and gas chromatography–mass spectrometry (GC-MS) methods were developed and validated for the determination of chlorambucil (CLB) and valproic acid (VPA) in plasma, as a part of experiments on their anticancer activity in c...

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Publicat a:Molecules
Autors principals: Lipska, Katarzyna, Gumieniczek, Anna, Pietraś, Rafał, Filip, Agata A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8153269/
https://ncbi.nlm.nih.gov/pubmed/34068372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26102903
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