Kinetics and Characterization of Degradation Products of Dihydralazine and Hydrochlorothiazide in Binary Mixture by HPLC-UV, LC-DAD and LC–MS Methods

Dihydralazine and hydrochlorothiazide were stored at high temperature and humidity, under UV/Vis light and different pH, as individual drugs and the mixture. Then, a sensitive and selective HPLC-UV method was developed for simultaneous determination of dihydralazine and hydrochlorothiazide in presen...

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Detalhes bibliográficos
Publicado no:Chromatographia
Main Authors: Gumieniczek, Anna, Galeza, Justyna, Mroczek, Tomasz, Wojtanowski, Krzysztof, Lipska, Katarzyna, Pietras, Rafał
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6132553/
https://ncbi.nlm.nih.gov/pubmed/30220731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-018-3555-8
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