Clinical significance of bax/bcl-2 ratio in chronic lymphocytic leukemia

In chronic lymphocytic leukemia the balance between the pro-apoptotic and anti-apoptotic members of the bcl-2 family is involved in the pathogenesis, chemorefractoriness and clinical outcome. Moreover, the recently proposed anti-bcl-2 molecules, such as ABT-199, have emphasized the potential role of...

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Détails bibliographiques
Publié dans:Haematologica
Auteurs principaux: Del Principe, Maria Ilaria, Bo, Michele Dal, Bittolo, Tamara, Buccisano, Francesco, Rossi, Francesca Maria, Zucchetto, Antonella, Rossi, Davide, Bomben, Riccardo, Maurillo, Luca, Cefalo, Mariagiovanna, De Santis, Giovanna, Venditti, Adriano, Gaidano, Gianluca, Amadori, Sergio, de Fabritiis, Paolo, Gattei, Valter, Del Poeta, Giovanni
Format: Artigo
Langue:Inglês
Publié: Ferrata Storti Foundation 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4697894/
https://ncbi.nlm.nih.gov/pubmed/26565002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2015.131854
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