Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells

BACKGROUND: ZAP-70 is an independent negative prognostic marker in chronic lymphocytic leukemia (CLL). Usually, its expression is investigated by flow cytometric protocols in which the percentage of ZAP-70 positive CLL cells is determined in respect to isotypic control (ISO-method) or residual ZAP-7...

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Detalhes bibliográficos
Main Authors: Rossi, Francesca M, Del Principe, Maria Ilaria, Rossi, Davide, Irno Consalvo, Maria, Luciano, Fabrizio, Zucchetto, Antonella, Bulian, Pietro, Bomben, Riccardo, Dal Bo, Michele, Fangazio, Marco, Benedetti, Dania, Degan, Massimo, Gaidano, Gianluca, Del Poeta, Giovanni, Gattei, Valter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846891/
https://ncbi.nlm.nih.gov/pubmed/20211015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-23
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