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Poly(ADP-ribose) polymerase-1 gene in human tumor cell lines: Its expression and structural alteration
Poly(ADP-ribose) polymerase-1 (Parp-1) is involved in DNA repair and cell-death induction after DNA damage. Parp-1(−/−) mice show higher susceptibility to the carcinogenic effects of nitrosamine and azoxymethane. To elucidate the role of alterations of the PARP-1 gene in human carcinogenesis, we exa...
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| 出版年: | Proc Jpn Acad Ser B Phys Biol Sci |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Japan Academy
2004
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8147301/ |
| タグ: |
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