Suppression of Gl Arrest and Enhancement of G2 Arrest by Inhibitors of Poly(ADP‐ribose) Polymerase: Possible Involvement of Poly(ADP‐ribosyl)ation in Cell Cycle Arrest Following γ‐Irradiation

Low‐dose γ‐irradiation of mouse embryonic fibroblast C3D2F1 3T3‐a cells caused Gl arrest along with G2 arrest and inhibition of replicative DNA synthesis. When the cells were cultured in the presence of inhibitors of poly(ADP‐ribose) polymerase [EC 2.4.2.30], such as 3‐aminobenzamide, benzamide and...

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Bibliografiske detaljer
Udgivet i:Jpn J Cancer Res
Main Authors: Nozaki, Tadashige, Masutani, Mitsuko, Akagawa, Tetsuya, Sugimura, Takashi, Esumi, Hiroyasu
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 1994
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5919371/
https://ncbi.nlm.nih.gov/pubmed/7829393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1994.tb02912.x
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