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Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells

Poly(ADP-ribose) polymerase-1 (Parp-1) localizes mainly in the nucleus and functions in DNA repair, genome stability and cell death regulation. Meanwhile, it also localizes in centrosomes and is involved in the regulation of centrosome duplication. An abnormal increase in centrosome numbers is frequ...

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Vydáno v:Proc Jpn Acad Ser B Phys Biol Sci
Hlavní autoři: Ogino, Hideki, Gunji, Akemi, Kamada, Nobuo, Nakagama, Hitoshi, Sugimura, Takashi, Masutani, Mitsuko
Médium: Artigo
Jazyk:Inglês
Vydáno: The Japan Academy 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8147680/
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