Inhibition of Poly (ADP-Ribose) Glycohydrolase Accelerates Osteoblast Differentiation in Preosteoblastic MC3T3-E1 Cells

Poly ADP-ribosylation (PARylation) is a post-translational modification catalyzed by poly (ADP-ribose) polymerase (PARP) family proteins such as PARP1. Although PARylation regulates important biological phenomena such as DNA repair, chromatin regulation, and cell death, little is known about the rel...

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Библиографические подробности
Главные авторы: Yuka Sasaki, Ryusuke Nakatsuka, Takuma Inouchi, Mitsuko Masutani, Tadashige Nozaki
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2022-05-01
Серии:International Journal of Molecular Sciences
Предметы:
PARP1
PARG
poly ADP-ribosylation
osteoblast differentiation
olaparib
PDD00017273
Online-ссылка:https://www.mdpi.com/1422-0067/23/9/5041
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