Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P(2) is required for autophagic lysosome reformation and protection from skeletal muscle disease

Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosom...

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Publicat a:Autophagy
Autors principals: Eramo, Matthew J., Gurung, Rajendra, Mitchell, Christina A., McGrath, Meagan J.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Autophagic Punctum
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143231/
https://ncbi.nlm.nih.gov/pubmed/33879025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1916195
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