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PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes

Phosphatidylinositol 4-kinase IIα (PtdIns4KIIα) localizes to the trans-Golgi network and endosomal compartments and has been implicated in the regulation of endosomal traffic, but the roles of both its enzymatic activity and the site of its action have not been elucidated. This study shows that PtdI...

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Pubblicato in:Mol Biol Cell
Autori principali: Henmi, Yuji, Morikawa, Yoshiaki, Oe, Natsuko, Ikeda, Narumi, Fujita, Akikazu, Takei, Kohji, Minogue, Shane, Tanabe, Kenji
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791142/
https://ncbi.nlm.nih.gov/pubmed/26823017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-08-0564
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