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Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P(2) is required for autophagic lysosome reformation and protection from skeletal muscle disease
Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosom...
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| Veröffentlicht in: | Autophagy |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8143231/ https://ncbi.nlm.nih.gov/pubmed/33879025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1916195 |
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