Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P(2) is required for autophagic lysosome reformation and protection from skeletal muscle disease

Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosom...

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Vydáno v:Autophagy
Hlavní autoři: Eramo, Matthew J., Gurung, Rajendra, Mitchell, Christina A., McGrath, Meagan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
Témata:
Autophagic Punctum
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143231/
https://ncbi.nlm.nih.gov/pubmed/33879025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1916195
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