Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P(2) is required for autophagic lysosome reformation and protection from skeletal muscle disease

Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosom...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Eramo, Matthew J., Gurung, Rajendra, Mitchell, Christina A., McGrath, Meagan J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2021
Materias:
Autophagic Punctum
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143231/
https://ncbi.nlm.nih.gov/pubmed/33879025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1916195
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