Bidirectional interconversion between PtdIns4P and PtdIns(4,5)P(2) is required for autophagic lysosome reformation and protection from skeletal muscle disease

Autophagic lysosome reformation (ALR) recycles autolysosome membranes formed during autophagy, to make lysosomes and is essential for continued autophagy function. Localized membrane remodeling on autolysosomes leads to the extension of reformation tubules, which undergo scission to form new lysosom...

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Bibliographic Details
Published in:Autophagy
Main Authors: Eramo, Matthew J., Gurung, Rajendra, Mitchell, Christina A., McGrath, Meagan J.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2021
Subjects:
Autophagic Punctum
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8143231/
https://ncbi.nlm.nih.gov/pubmed/33879025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2021.1916195
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