Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loops

Pathogenic DNA secondary structures have been identified as a common and causative factor for expansion in trinucleotide, hexanucleotide, and other simple sequence repeats. These expansions underlie about fifty neurological and neuromuscular disorders known as “anticipation diseases”. Cell toxicity...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Comput Struct Biotechnol J
Główni autorzy: Pan, Feng, Zhang, Yuan, Xu, Pengning, Man, Viet Hoang, Roland, Christopher, Weninger, Keith, Sagui, Celeste
Format: Artigo
Język:Inglês
Wydane: Research Network of Computational and Structural Biotechnology 2021
Hasła przedmiotowe:
Review
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138726/
https://ncbi.nlm.nih.gov/pubmed/34093995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.037
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