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Molecular conformations and dynamics of nucleotide repeats associated with neurodegenerative diseases: double helices and CAG hairpin loops
Pathogenic DNA secondary structures have been identified as a common and causative factor for expansion in trinucleotide, hexanucleotide, and other simple sequence repeats. These expansions underlie about fifty neurological and neuromuscular disorders known as “anticipation diseases”. Cell toxicity...
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| 出版年: | Comput Struct Biotechnol J |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Research Network of Computational and Structural Biotechnology
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8138726/ https://ncbi.nlm.nih.gov/pubmed/34093995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.037 |
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