Structure and Dynamics of DNA and RNA Double Helices of CAG and GAC Trinucleotide Repeats

CAG trinucleotide repeats are known to cause 10 late-onset progressive neurodegenerative disorders as the repeats expand beyond a threshold, whereas GAC repeats are associated with skeletal dysplasias and expand from the normal five to a maximum of seven repeats. The TR secondary structure is believ...

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Vydáno v:Biophys J
Hlavní autoři: Pan, Feng, Man, Viet Hoang, Roland, Christopher, Sagui, Celeste
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2017
Témata:
Nucleic Acids and Genome Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510815/
https://ncbi.nlm.nih.gov/pubmed/28700917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.05.041
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