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E-motif formed by extrahelical cytosine bases in DNA homoduplexes of trinucleotide and hexanucleotide repeats

Atypical DNA secondary structures play an important role in expandable trinucleotide repeat (TR) and hexanucleotide repeat (HR) diseases. The cytosine mismatches in C-rich homoduplexes and hairpin stems are weakly bonded; experiments show that for certain sequences these may flip out of the helix co...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Pan, Feng, Zhang, Yuan, Man, Viet Hoang, Roland, Christopher, Sagui, Celeste
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778509/
https://ncbi.nlm.nih.gov/pubmed/29190385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1186
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