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E-motif formed by extrahelical cytosine bases in DNA homoduplexes of trinucleotide and hexanucleotide repeats

Atypical DNA secondary structures play an important role in expandable trinucleotide repeat (TR) and hexanucleotide repeat (HR) diseases. The cytosine mismatches in C-rich homoduplexes and hairpin stems are weakly bonded; experiments show that for certain sequences these may flip out of the helix co...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Pan, Feng, Zhang, Yuan, Man, Viet Hoang, Roland, Christopher, Sagui, Celeste
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778509/
https://ncbi.nlm.nih.gov/pubmed/29190385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1186
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