A carregar...
Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids
Expansion of the GAA/TTC repeats in the first intron of the FXN gene causes Friedreich’s ataxia. Non-canonical structures are linked to this expansion. DNA triplexes and R-loops are believed to arrest transcription, which results in frataxin deficiency and eventual neurodegeneration. We present a sy...
Na minha lista:
| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7515735/ https://ncbi.nlm.nih.gov/pubmed/32821947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa665 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|