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Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA•TTC) associated with Friedreich’s ataxia

Expansion of certain trinucleotide repeats causes several types of human diseases, and such tracts are associated with the formation of deletions and other types of genetic rearrangements in Escherichia coli, yeast, and mammalian cells. Below, we show that long (230 repeats) tracts of the trinucleot...

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書誌詳細
主要な著者: Tang, Wei, Dominska, Margaret, Gawel, Malgorzata, Greenwell, Patricia W., Petes, Thomas D.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534863/
https://ncbi.nlm.nih.gov/pubmed/23182423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.001
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