Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA•TTC) associated with Friedreich’s ataxia

Expansion of certain trinucleotide repeats causes several types of human diseases, and such tracts are associated with the formation of deletions and other types of genetic rearrangements in Escherichia coli, yeast, and mammalian cells. Below, we show that long (230 repeats) tracts of the trinucleot...

Full description

Saved in:
Bibliographic Details
Main Authors: Tang, Wei, Dominska, Margaret, Gawel, Malgorzata, Greenwell, Patricia W., Petes, Thomas D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534863/
https://ncbi.nlm.nih.gov/pubmed/23182423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.001
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items