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Genomic deletions and point mutations induced in Saccharomyces cerevisiae by the trinucleotide repeats (GAA•TTC) associated with Friedreich’s ataxia

Expansion of certain trinucleotide repeats causes several types of human diseases, and such tracts are associated with the formation of deletions and other types of genetic rearrangements in Escherichia coli, yeast, and mammalian cells. Below, we show that long (230 repeats) tracts of the trinucleot...

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Bibliografske podrobnosti
Main Authors: Tang, Wei, Dominska, Margaret, Gawel, Malgorzata, Greenwell, Patricia W., Petes, Thomas D.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3534863/
https://ncbi.nlm.nih.gov/pubmed/23182423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.10.001
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