Llwytho...

Super-enhancer-mediated core regulatory circuitry in human cancer

Super-enhancers (SEs) are congregated enhancer clusters with high level of loading of transcription factors (TFs), cofactors and epigenetic modifications. Through direct co-occupancy at their own SEs as well as each other’s, a small set of so called “master” TFs form interconnected core regulatory c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Comput Struct Biotechnol J
Prif Awduron: Jiang, Yuan, Jiang, Yan-Yi, Lin, De-Chen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Research Network of Computational and Structural Biotechnology 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138668/
https://ncbi.nlm.nih.gov/pubmed/34093993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.05.006
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