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Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma
Lung adenocarcinoma (LUAD) relies on dysregulated gene expression to sustain its infinite growth and progression. Emerging evidence indicates that aberrant transcriptional program results from core transcriptional regulatory circuitry (CRC) which is driven by super-enhancers (SEs). In this study, by...
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| Pubblicato in: | Oncogenesis |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568720/ https://ncbi.nlm.nih.gov/pubmed/33070167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00277-9 |
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