Core transcriptional regulatory circuitry in human hepatocytes

We mapped the transcriptional regulatory circuitry for six master regulators in human hepatocytes using chromatin immunoprecipitation and high-resolution promoter microarrays. The results show that these regulators form a highly interconnected core circuitry, and reveal the local regulatory network...

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Autors principals: Odom, Duncan T, Dowell, Robin D, Jacobsen, Elizabeth S, Nekludova, Lena, Rolfe, P Alexander, Danford, Timothy W, Gifford, David K, Fraenkel, Ernest, Bell, Graeme I, Young, Richard A
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1681491/
https://ncbi.nlm.nih.gov/pubmed/16738562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100059
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