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Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma

Lung adenocarcinoma (LUAD) relies on dysregulated gene expression to sustain its infinite growth and progression. Emerging evidence indicates that aberrant transcriptional program results from core transcriptional regulatory circuitry (CRC) which is driven by super-enhancers (SEs). In this study, by...

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Bibliografiska uppgifter
I publikationen:Oncogenesis
Huvudupphovsmän: Zhang, Te, Song, Xuming, Zhang, Zeyu, Mao, Qixing, Xia, Wenjie, Xu, Lin, Jiang, Feng, Dong, Gaochao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568720/
https://ncbi.nlm.nih.gov/pubmed/33070167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00277-9
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