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Aberrant super-enhancer landscape reveals core transcriptional regulatory circuitry in lung adenocarcinoma

Lung adenocarcinoma (LUAD) relies on dysregulated gene expression to sustain its infinite growth and progression. Emerging evidence indicates that aberrant transcriptional program results from core transcriptional regulatory circuitry (CRC) which is driven by super-enhancers (SEs). In this study, by...

詳細記述

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書誌詳細
出版年:Oncogenesis
主要な著者: Zhang, Te, Song, Xuming, Zhang, Zeyu, Mao, Qixing, Xia, Wenjie, Xu, Lin, Jiang, Feng, Dong, Gaochao
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568720/
https://ncbi.nlm.nih.gov/pubmed/33070167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00277-9
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